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April 14, 2006, Newsletter Issue #11: The Bextra debate
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Tip of the Week
The lack of variable dosages in Bextra has raised concerns about how it is used. According to the American Medical Association, the range of response to a drug can vary from one person to another by four to forty-fold. This is not surprising; people's ages, sizes, absorption and metabolism of medications, other concomitant medical disorders, innate sensitivities to medications, and other drugs being used will have an impact. Medical science supports using the lowest, safest, proven-effective doses of drugs, particularly for NSAIDs, yet such individualization was not possible with one-size-fits-all Bextra. Whether you were 25 or 95 years old, 100 or 300 pounds, your doctor prescribed 10 mg of Bextra for your osteoarthritis. This is not only bad medicine, but also defies published studies on Bextra.
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