December 4, 2009, Newsletter Issue #49: How has Pfizer reacted to claims that Bextra is unsafe?

Tip of the Week

Pfizer, the manufacturer of Bextra, claims that no substantive evidence of Bextra cardiovascular side effects was discovered in clinical trials. The earliest Bextra warning statements were made at an American Heart Association meeting in early November 2004. They cited studies showing an increase of cardiovascular side effects for Bextra users who underwent cardiac bypass surgery. Later, a New York Times article appeared stating that Bextra may have adverse effects on cardiovascular health. Pfizer retorted by stating that none of these findings are substantiated and that the company intends on initiating long term studies on the long term effects of Bextra on cardiovascular health. The FDA also plans on conducting studies on the effects of all COX-2 selective on cardiovascular health.

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