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Bextra warning statements have already been included in Bextra labeling information. Bextra causes rare but serious skin diseases in some patients who take it. Bextra warning statements indicate that Bextra side effects may include Stevens-Johnson syndrome, a rare skin condition characterized by a severe inflammatory eruption of the skin and mucous membranes. Toxic epidermal necrolysis is also a potential side effect of taking Bextra. This skin condition causes large portions of the skin to become red and peel in the manner similar to a second degree burn. Bextra warnings also caution that Bextra can cause severe allergic reactions in some patients, including anaphylactic shock.