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A Bextra stroke is a possible side effect of taking this popular prescription painkiller. A Bextra stroke is just one of the many serious and potentially deadly side effects that prompted the FDA to request a recall of this drug. On April 7, 2005, Pfizer took its blockbuster painkiller, Bextra, off the market because the risks associated with Bextra far outweigh the drug's intended benefits.